1st Edition
Advances in Immunological Treatment of Cancer Cellular Mechanism and Regulations
Improvement in understanding of immune suppression mechanisms in the human body has revolutionized the way cancer is perceived and treated. The new book, Advances in Immunological Treatment of Cancer: Cellular Mechanism and Regulations, provides a clinically relevant overview of cancer immunology and immunotherapy. It explores the cutting-edge research behind cancer’s driving mechanism of immune suppression, as well as some cutting-edge therapeutic approaches to combating cancer. This book offers novel approaches to cancer therapy with a special emphasis on the emerging new principles of immune suppression that drive the disease. Further, the book explains the fundamental principles of immune suppression that are driving research in this area. It also shows that conventional chemotherapeutic drugs and molecularly targeted therapeutics can both have significant anti-tumor effects in animal models. The book comprehensively covers the immune escape as a critical trait in cancer and how specific combinations of immunotherapy and chemotherapy can be used to attack this trait.
The book focuses on the emerging new principles of immune suppression that drive cancer and provides radical new ideas for improving therapy by employing these principles. It also demonstrates the use and effectiveness of conventional chemotherapeutic drugs in eliminating tumors. The book provides an overview of immunoregulation via allogeneic stem cell transplantation and also discusses the various resistance mechanisms in cancer immunology. It offers new hope for survival via immunoediting and details the development of antigen and phenotypic plasticity molecules for cancer immunotherapy.
The authors discuss toll-like receptors and detail self-to-tumor immune interactions. Methods for reducing tumor growth and altering tumor immunogenicity are also discussed along with the many ways in which conventional chemotherapy can boost the immune system. The function of innate and adaptive immunity in immune vigilance is also explored.
This book is a must-read for researchers in basic, translational, and clinical cancer fields, as it provides a comprehensive overview of the immune escape process as a critical trait in cancer and how targeted combinations of immunotherapy and chemotherapy to combat this trait may significantly improve the treatment of cancer.
Foreword by Kamla Pathak
1. Introduction of Immunoregulation Through Allogeneic Stem Cell Transfusion
2. Resistance Mechanisms in Cancer Immunology
3. Cancer Immunoediting: A New Hope for Survival
4. Understanding of Antigens and Phenotypic Plasticity Molecules for the Purpose of Cancer Immunotherapy
5. Regulatory T Cells in Tumor Immunity: Role of Toll-Like Receptors
6. Cancer Immunotherapy: Understanding Immune Tolerance
7. Immunity‘s Role in Suppressing Tumor Growth and Shaping Tumor Immunogenicity
8. The Immune Stimulating Effects of Conventional Chemotherapy
9. The Role of Innate and Adaptive Antitumor Immunity in Immune Surveillance
Biography
Rishabha Malviya, PhD, has 12 years of research experience and is presently working as Associate Professor in the Department of Pharmacy, School of Medical and Allied Sciences, Galgotias University, India. His areas of interest include formulation optimization, nanoformulation, targeted drug delivery, localized drug delivery, and characterization of natural polymers as pharmaceutical excipients. He has authored more than 150 research and review papers for national and international journals of repute. He has authored and edited over 40 books and over 30 book chapters published by Scrivener Publishing, Wiley, CRC Press/Taylor and Francis, Springer, River Publisher, Apple Academic Press, IOP, and others. His cumulative impact factor is 190. He has over 50 patents to his name. Dr. Malviya has received an Outstanding Reviewer Award from Elsevier. His name has been included in the Stanford University’s World’s Top 2% Scientists, 2020, by Elsevier BV and Stanford University. He is reviewer, editor, and editorial board member of more than 50 national and international journals. He was an invited author for the magazine Atlas of Science as well as a pharma magazine dealing with the B2B industry, Ingredients South Asia. He completed his BPharm at Uttar Pradesh Technical University and MPharm (Pharmaceutics) at Gautam Buddha Technical University, Lucknow, Uttar Pradesh, India. His PhD (Pharmacy) work was in novel formulation development techniques.
Arun Kumar Singh, MPharm, is affiliated with the Department of Pharmacy, School of Medical & Allied Sciences, Galgotias University, Greater Noida, Uttar Pradesh, India. His areas of interest include nanoformulation, blockchain, IoT, machine learning, cancer, artificial intelligence, and big data. He has authored four books with Scrivener Publishing/Wiley, IOP publishing and Apple Academic Press/Taylor and Francis Groups. He has published five chapters with renowned international publishers. He has also published more than eight SCI papers with total 43 cumulative impact factor. His strength is his research skill, innovative thinking, leadership qualities, decision-making ability, and positive thinking.
Deepika Yadav, MPharm, earned her BPharm from K R Mangalam University, Gurugram, Haryana and MPharm from Galgotias University, Greater Noida, India. She has authored two books with Apple Academic Press/ Taylor and Francis Group and Scrivener Publishing/Wiley as well as book chapters with other reputed international publishers. She is also working on two books with other renowned international publishers.
"A must-read for basic, translational, and clinical researchers looking to improve the treatment of advanced disease. . . This book will be useful to its readers because it provides a comprehensive analysis of immunology‘s potential role in the fight against cancer, the system‘s role in regulating tumor growth, and the impact of the immune system on tumor immunogenicity."
—From the Foreword by Kamla Pathak, PhD, Dean, Faculty of Pharmacy, Uttar Pradesh University of Medical Sciences, India
