1st Edition
Antioxidants as Nutraceuticals
Antioxidants and nutraceuticals have gained significant attention in recent years due to their potential to protect against diseases and improve overall health. This new volume explores the exciting and rapidly growing field of natural compounds with health-promoting properties.
Providing a comprehensive overview of antioxidants and nutraceuticals, including their sources, mechanisms of action, and health benefits, the volume covers the latest research on a range of antioxidants and nutraceuticals, including vitamins, minerals, and phytochemicals, and provides practical information on their safe and effective use. The book also addresses the challenges and controversies surrounding the use of antioxidants and nutraceuticals and provides guidance on their selection and use.
The volume first covers the basics of types of antioxidants as nutraceuticals, including the importance of phytochemical antioxidants and the nutritional and pharmacological intervention in the treatment of disease. It discusses the natural origins of antioxidants, classification, mechanism of action, calculation of antioxidant potential of nutraceutical substances, safety, toxicity, and their significant involvement in the prevention of many degenerative and chronic diseases.
The volume presents novel strategies of antioxidants in the treatment of chronic diseases, such as cardiovascular disease, chronic inflammatory diseases, neurodegenerative disorders, and diabetes mellitus. Chapters also look at a variety of functional foods that are rich in antioxidants.
PART I: BASICS OF TYPES OF ANTIOXIDANTS AS NUTRACEUTICALS
1. Natural Antioxidants as Nutraceuticals
Dattatraya M. Shinkar, Amit B. Page, Prashant S. Malpure, Bhushan Rane, and Prashant L. Pingale
2. Importance of Phytochemical Antioxidants
Yogeeta Goyal, Mrunali Patil, Kamini More, and Kiran Patil
3. Epigallocatechin Gallate: Nutritional and Pharmacological Intervention in the Treatment of Diseases
Myrene Roselyn D‘souza and Khalid Mohammed Naji
4. Immunomodulatory Property of Antioxidants
Kiran Patil, Sopan Nangare, Meghanath Shete, Madhav Shelke, Matin Shaikh, Mrugendra Potdar, Vinit Agnihotri, and Yogeeta Goyal
PART II: NOVEL STRATEGIES OF ANTIOXIDANTS IN THE TREATMENT OF CHRONIC DISEASES
5. Antioxidants as Nutraceutical in Prevention and Treatment of Cardiovascular Diseases
Amey Sukhia, Nayan A. Gujarathi, Tulshidas S. Patil, Abhijeet Aher, Bhushan Rane, and Raj K. Keservani
6. Novel Strategies of Antioxidants in Chronic Inflammatory Diseases
Sumit Rathod, Ujwal Katolkar, Vinit Agnihotri, Mrugendra Potdar, and Yogeeta Goyal
7. Plant-Derived Antioxidant Nutraceuticals for the Treatment of Neurodegenerative Disorders
Prashant Amale, Kushagra Nagori, Hemant Badwaik, Madhuri Baghel, and Kartik Nakhate
8. Nutraceutical Antioxidants in the Prevention and Treatment of Diabetes Mellitus
Neha Panchabhai, Harshad Jadhav, Sanjiri Dilip Shelar, Amey Sukhia, Nayan A. Gujarathi, and Raj K. Keservani
PART III: FUNCTIONAL FOODS RICH IN ANTIOXIDANTS
9. Antioxidants as Rich Food Sources of Nutraceutical and Functional Foods
Sujit Arun Desai, Preeti Khulbe, Yuvraj Dilip Dange, Satwashila Kadam, and Meenakshi Jaiswal
10. Anti-Stress Functional Foods
Neelesh Kumar Maurya, Latika Yadav, Pratibha Arya, Abhijeet Aher, and Nayan A. Gujarathi
11. An Update on the Role of Antioxidants in Health and Disease Prevention
Mrugendra Bhojraj Potdar, Kiran Patil, Md. Rageeb, Md. Usman, and Raju Ratan Wadekar
Biography
Nayan A. Gujarathi, PhD, MPharm, is an Associate Professor at the Department of Pharmaceutics, Shri Vile Parle Kelavani Mandal‘s Institute of Pharmacy, Dhule, India. He has 16 years of academic experience in pharmaceutical science. He has published 24 peer-reviewed papers in the field of pharmaceutical sciences in national and international journals with 12 book chapters in Apple Academic Press/CRC Press books. He has presented his research work at an international conference organized by the Controlled Release Society and delivered four expert talks on the implementation of outcome-based education for the accreditation process. He is an approved postgraduate teacher in pharmaceutics by North Maharashtra University, Jalgaon, and Savitribai Phule University, Pune, both in India. He successfully guided 24 MPharm students of Pharmaceutics. He has been appointed as a referee (evaluator) at the university level for Avishkar 2013 and Avishkar 2017 by North Maharashtra University, Jalgaon. He completed a minor research project sanctioned by BCUD, North Maharashtra University, Jalgaon. His research interest encompasses novel drug delivery systems, polymer science, nanotechnology, and nutraceuticals. He received a diploma in Pharmacy from the Government Polytechnic, Jalgaon, India, and a bachelor‘s degree in pharmacy from the North Maharashtra University. He completed a Master of Pharmacy degree with a specialization in pharmaceutics at the School of Pharmaceutical Sciences, Rajiv Gandhi Proudyogiki Vishwavidyalaya, Bhopal, India. He was awarded his PhD in pharmaceutical sciences by Jodhpur National University, Jodhpur, India.
Raj K. Keservani, MPharm, is Associate Professor in the Faculty of B. Pharmacy, CSM Group of Institutions, Allahabad, India. He has more than 12 years of academic (teaching) experience at various institutes of India, imparting pharmaceutical education. He has published many peer-reviewed papers in the field of pharmaceutical sciences in national and international reputed journals, book chapters, coauthored books, and edited books. He is also active as a reviewer for several international scientific journals. His research interests encompass nutraceutical and functional foods, novel drug delivery systems (NDDS), transdermal drug delivery/drug delivery, health science/life science, and biology/cancer biology/neurobiology. Mr. Keservani graduated (BPharm) from the Department of Pharmacy, Kumaun University, Nainital, Uttarakhand, India, in 2005. Afterward, he qualified GATE in the same year, conducted by IIT Mumbai. He received his Master of Pharmacy from the School of Pharmaceutical Sciences, Rajiv Gandhi Proudyogiki Vishwavidyalaya, Bhopal, Madhya Pradesh, India, in 2008 with a specialization in pharmaceutics.
Rajesh K. Kesharwani, PhD, is working as Associate Professor in the Department of Computer Application, Nehru Gram Bharati (Deemed to be University), Prayagraj, India. He has more than 11 years of research and nine years of teaching experience at various institutes of India, imparting bioinformatics and biotechnology education. He has received several awards, including the NASI-Swarna Jayanti Puruskar by The National Academy of Sciences of India. He has supervised one PhD and more than 20 undergraduate and graduate students for their research work. Dr. Kesharwani has authored over 49 peer-reviewed articles, 20 book chapters, and 14 edited books with international publishers. He has been a member of many scientific communities as well as a reviewer for many international journals. He has presented many papers at various national and international conferences. He has been a recipient of a Ministry of Human Resource Development (India) Fellowship and a Senior Research Fellowship from the Indian Council of Medical Research, India. His research fields of interest are medical informatics, protein structure and function prediction, computer-aided drug designing, structural biology, drug delivery, cancer biology, nanobiotechnology, and biomedical sciences. Dr. Kesharwani received his PhD from the Indian Institute of Information Technology, Allahabad, and worked at NIT Warangal for two semesters.
Bhushan R. Rane, PhD, MPharm, is presently Professor and Head of the Department of Pharmaceutics, Shri. D. D. Vispute, College of Pharmacy and Research Center, New Panvel, Navi Mumbai, India, affiliated to Mumbai University, Maharashtra, India. He has over 15 years of teaching experience at undergraduate and postgraduate levels. To date, he has guided more than 50 students for their MPharm degrees. He has published more than 75 peer-reviewed research and review articles in national and international journals. He has co-authored eight books at the national level and more than 15 book chapters at the international level published by Taylor and Francis Group and Bentham Science Worldwide. He is a reviewer for several scientific and international journals. He received grants from various bodies for research, such as All India Council for Technical Education (AICTE), New Delhi. He is a lifetime member of several professional organizations. His research interests are focused on planning, improvement, and the portrayal of vesicular, microparticulate, and nanoparticulate systems, and advancement of different solid dosage forms for oral conveyance.
Yogeeta Goyal Agrawal, PhD, MPharm, is an Associate Professor and Head of the Department of Pharmaceutics at Shri Vile Parle Kelavani Mandal‘s Institute of Pharmacy, Dhule, India. She has 17 years of research and academic experience in pharmaceutical science. She has published 29 peer-reviewed papers in national and international journals. Her h-index is 12 and i10-index is 13. She has published patents at the Indian patent office. She is an approved postgraduate teacher and PhD guide in pharmaceutics by North Maharashtra University, Jalgaon, India. She has successfully guided 25 students for their MPharm degrees and is currently guiding six PhD students. She has successfully completed a major research project sanctioned by the Department of Biotechnology, Govt of India. She received several awards for her work, including gold medals for earning the highest marks at both the BPharm and MPharm levels. She received two minor projects from Kavayitri Bahinabai Chaudhari North Maharashtra University for her research work. She also received a complete international travel grant from the Indian Council of Medical Research (ICMR) to present her research work at an international conference in Dubai. She has participated as delegate and resource person in several workshops and conferences. Her research interests encompass novel drug delivery systems, especially formulation, development, optimization, and in-vitro and in-vivo evaluation of nanostructured lipid carrier.
