1st Edition

Atlas of Corneal Imaging

By J. Bradley Randleman Copyright 2022

    A comprehensive reference for physicians, surgeons, and trainees, Atlas of Corneal Imaging covers all aspects of corneal imaging from basic map interpretation to advanced diagnostic uses and features over 1200 illustrative images and figures representing a wide variety of devices and techniques.

    Drs. J. Bradley Randleman, Marcony Santhiago, and William J. Dupps Jr guide readers through the process of analyzing corneal images using a multitude of different techniques, technologies, and individual devices. This creates a complete picture of the cornea’s basic methods and pathological processes and allows readers to directly visualize how their technology would display the pathology in question.

    Atlas of Corneal Imaging is designed to help practitioners recognize subtle findings and evaluate signs of weakening or pathology, no matter how they present or what device is being used. Multiple iterations of the same clinical condition are shown with numerous complementary images for the same eye to provide a comprehensive presentation of each case.

    Chapters feature information on:

    • Topographic patterns and mapping
    • Corneal ectasia evaluations
    • Cornea and refractive surgery evaluations
    • Clinical correlations with corneal disorders
    • Cornea and refractive surgery complications
    • Evaluation for cataract surgery

    Atlas of Corneal Imaging fills a significant void in corneal imaging resources available today by presenting an image-first approach to understanding all the many different technologies for imaging the cornea.

    Dedication

    Acknowledgments

    About the AuthorAbout the Associate Editors

    Contributing Authors

    Foreword by Stephen D. Klyce, PhDIntroduction

    Chapter 1 Fundamental Concepts in Corneal ImagingMehdi Roozbahani, MD; Marcony R. Santhiago, MD, PhD; William J. Dupps, MD, PhD;and J. Bradley Randleman, MD Basic Definitions and Terminology Confusing Clinical Concepts Imaging Devices Placido-Based Reflection Devices LED-Based Reflective Devices Tomography-Based Imaging Devices Slit Scanning-Based Tomography Scheimpflug-Based Tomographers Optical Coherence Tomography Very High–Frequency Digital Ultrasound Aberrometers for Wavefront Analysis Summary

    Chapter 2 Corneal Imaging Devices: Applications and Set Up Mehdi Roozbahani, MD; Marcony R. Santhiago, MD, PhD; William J. Dupps, MD, PhD;and J. Bradley Randleman, MD Basic Device Set Up Specific Imaging Devices Placido Topography Scanning Slit Imaging (Orbscan II) Scheimpflug Imaging (Pentacam) Dual Scheimpflug/Placido Imaging (Galilei) Scheimpflug/Placido Imaging (Sirius) Anterior Segment Optical Coherence Tomography Very High–Frequency Digital Ultrasound Imaging Artifacts Summary

    Chapter 3 Basic Topographic Patterns and Tomographic Correlates J. Bradley Randleman, MD; Marcony R. Santhiago, MD, PhD; and William J. Dupps, MD, PhD Notes on Maps in This

    Section

    Section 1: Symmetric Nonastigmatic Patterns (Normal Patterns and Variants)

    Section 2: Symmetric Astigmatic Patterns (Normal Variants)

    Section 3: Asymmetric Astigmatic Patterns (Suspicious Patterns)

    Section 4: Abnormal Asymmetric Patterns Against-the-Rule Astigmatism Inferior Steepening Focally Steep Patterns Skewed Radial Axes Asymmetric Bowtie With Skewed Radial Axis Pattern Truncated Bowtie Pattern Vertical D Pattern Drooping D Pattern Pellucid Marginal Degeneration–Like (Crab Claw) Pattern

    Section 5: Keratometry/Topography Relationship in Ectatic Corneas

    Chapter 4 Epithelial Mapping J. Bradley Randleman, MD; Marcony R. Santhiago, MD, PhD; and William J. Dupps, MD, PhD Epithelial Thickness and Remodeling Patterns

    Section 1: General Epithelial Mapping Images in Normal Eyes

    Section 2: Epithelial Mapping in Keratoconus

    Section 3: Epithelial Mapping in Refractive Surgery Screening

    Section 4: Epithelial Mapping After Refractive Surgery

    Section 5: Irregular Epithelial Mapping With Corneal Irregularities

    Chapter 5 Corneal Ectasia Evaluations J. Bradley Randleman, MD; Marcony R. Santhiago, MD, PhD; and William J. Dupps, MD, PhD Progressively Advanced Presentations of Corneal Ectasias

    Section 1: Corneal Ectasia Suspects

    Section 2: Keratoconus Highly Asymmetric (Clinically Unilateral) Keratoconus Asymmetric Keratoconus Mild Keratoconus Moderate Keratoconus Severe Keratoconus Atypical Keratoconus Images Stable Keratoconus Progressive Keratoconus Corneal Hydrops

    Section 3: Pellucid Marginal Corneal Degeneration

    Section 4: Postoperative Corneal Ectasia

    Chapter 6 Corneal Imaging in Refractive Surgery Evaluations J. Bradley Randleman, MD; Marcony R. Santhiago, MD, PhD; and William J. Dupps, MD, PhD Note on Screening Recommendations

    Section 1: Suitable Refractive Surgery Candidates: Normal Imaging and Variants

    Section 2: Suspicious Imaging in Refractive Surgery Evaluations

    Section 3: Abnormal Imaging in Refractive Surgery Evaluations

    Section 4: Ectasia After LASIK Cases: Preoperative Corneal Imaging

    Chapter 7 Postoperative Patterns After Corneal and Refractive Surgery J. Bradley Randleman, MD; Marcony R. Santhiago, MD, PhD; and William J. Dupps, MD, PhD

    Section 1: Keratoplasty

    Section 2: Incisional Refractive Surgery

    Section 3: LASIK

    Section 4: Photorefractive Keratectomy

    Section 5: Small Incision Lenticule Extraction

    Section 6: Phakic Intraocular Lens

    Section 7: Intracorneal Ring Segments

    Section 8: Orthokeratology

    Section 9: Corneal Cross-Linking Imaging

    Section 10: Therapeutic Topography-Guided Ablations

    Chapter 8 Corneal and Refractive Surgery Complications J. Bradley Randleman, MD; Marcony R. Santhiago, MD, PhD; and William J. Dupps, MD, PhD

    Section 1: Ablation Issues

    Section 2: LASIK Flap Complications

    Section 3: Interface Complications

    Section 4: Ocular Surface Complications

    Section 5: Complications After Incisional Refractive Surgery

    Section 6: Complications After Intracorneal Ring Segments Implantation

    Section 7: Phakic Intraocular Lens Complications

    Section 8: Complications After Keratoplasty

    Chapter 9 Clinical/Topographic Correlations J. Bradley Randleman, MD; Marcony R. Santhiago, MD, PhD; and William J. Dupps, MD, PhD

    Section 1: Dry Eye

    Section 2: Corneal Scarring Resulting From Infectious Keratitis

    Section 3: Epithelial Basement Membrane Dystrophy

    Section 4: Salzmann's Nodular Degeneration

    Section 5: Pterygium

    Section 6: Fuchs' Corneal Dystrophy

    Section 7: Corneal Stromal Dystrophies

    Section 8: Limbal Stem Cell Deficiency

    Section 9: Floppy Eyelid Syndrome

    Chapter 10 Corneal Imaging for Evaluations of Patients With Cataracts J. Bradley Randleman, MD; Marcony R. Santhiago, MD, PhD; and William J. Dupps, MD, PhD

    Section 1: Routine Cataract Evaluations

    Section 2: Toric Intraocular Lens Evaluations

    Section 3: Cataract Evaluations in Patients With Prior Laser Vision Correction

    Section 4: Cataract Evaluations in Patients With Prior Radial Keratotomy

    Section 5: Cataract Evaluations in Patients With KeratoconusFinancial Disclosures

    Index

    Biography

    J. Bradley Randleman, MD is a Professor in the Department of Ophthalmology at the Cleveland Clinic Lerner College of Medicine of Case Western Reserve University and Staff Ophthalmologist and Co-Director of the Refractive Surgery Section at the Cole Eye Institute of the Cleveland Clinic Foundation in Cleveland, Ohio. Prior to his arrival in Cleveland, Dr. Randleman was Professor of Ophthalmology at the Keck School of Medicine of University of Southern California and Director of the Cornea & Refractive Surgery Service at the University of Southern California Roski Eye Institute in Los Angeles, California, and the Hughes Professor of Ophthalmology at Emory University and Director of the Cornea Section at the Emory Eye Center. A widely respected cornea specialist, his areas of expertise include corneal and intraocular (IOL) refractive surgical procedures, including LASIK and premium cataract and IOL surgery, complicated cataract surgery, and the management of corneal ectatic disorders. His primary research focuses on identification and management of corneal ectatic diseases, including keratoconus and postoperative ectasia after LASIK, and the avoidance, diagnosis, and management of refractive surgical complications. He has been awarded multiple research grants throughout his career, including R01 funding from the National Institutes of Health to evaluate corneal biomechanical analysis using Brillouin microscopy.

    Dr. Randleman received his BA degree from Columbia College at Columbia University in New York City; his MD degree from Texas Tech University School of Medicine in Lubbock, Texas, where he was elected to the Alpha Omega Alpha medical honor society in his junior year; and followed by his Ophthalmology residency and fellowship in Cornea/External Disease, and Refractive Surgery at Emory University in Atlanta, Georgia.

    Dr. Randleman has been awarded the Claus Dohlman Fellow Award, the inaugural Binkhorst Young Ophthalmologist Award from the American Society of Cataract and Refractive Surgery, the Kritzinger Memorial Award, Founder’s Award, President’s Award, and the Inaugural Recognition Award from the International Society of Refractive Surgery, and the Secretariat Award, Achievement Award, and Senior Achievement Award from the American Academy of Ophthalmology. He was named to The Power List by The Ophthalmologist in both 2018 and 2020.

    Dr. Randleman has served as Editor-in-Chief for the Journal of Refractive Surgery since 2011. He has authored more than 165 peer-reviewed publications in leading ophthalmology journals in addition to 40 book chapters on refractive surgery evaluation, corneal cross-linking, and management of complications with IOLs, and has authored 4 previous textbooks, Corneal Collagen Cross-Linking; Corneal Cross-Linking, Second Edition; Refractive Surgery: An Interactive Case-Based Approach; and Intraocular Lens Surgery: Selection, Complications, and Complex Cases.