1st Edition
Biosensors Based on Graphene, Graphene Oxide and Graphynes for Early Detection of Cancer
The detection of cancer at its earliest stages is paramount for successful treatment and improved patient outcomes. In recent years, the field of nanotechnology has witnessed significant advancements, and one material that has emerged as a potential game-changer in cancer detection is graphene. Graphene's high surface area, excellent electrical conductivity, and ability to interact with biological molecules have paved the way for innovative approaches to diagnosing cancer. Moreover, graphene oxide, a derivative of graphene, has gained significant attention in the field of cancer detection. Its unique properties, including biocompatibility and high photothermal conversion efficiency, enable its use in various imaging techniques. Graphene oxide can selectively accumulate in tumor tissues, enhancing the contrast signals in imaging modalities like optical imaging, magnetic resonance imaging (MRI), and photoacoustic imaging. This allows for precise visualization and localization of cancerous cells or tissues, aiding in early detection and accurate diagnosis.
Features:
- Provide a comprehensive exploration of carbon, its allotropes, and its significance in emerging applications.
- Discuss the synthesis and functionalization of graphene on diverse substrates, and modeling approaches employed in graphene research.
- Detailed the application of Graphene, GO, and Graphyne based materials on cancer detection.
- Explores the overview of the wider biological applications of carbon-based materials.
The proposed book will serve as a valuable reference source for researchers, academics, and biologists working in R&D and interested in biosensing for the early detection of cancer.
Chapter 1 Carbon Allotropes: Past to Present Aspects
Chandra Shekhar Yadav, Iqbal Azad, Abdul Rahman Khan,and Prashant Singh
Chapter 2 Carbon Nanostructure
Priya Chaudhary, Ayushi Prajapat, and Kamlesh Kumari
Chapter 3 Role of Functional Carbon Nanostructure in the Biomedical applications
Kunvar Pratap Nishad, Durgesh Chauhan, Ankur Prajapati, Rahul Kushwaha, and Azad Kumar
Chapter 4 Effects of Nanodiamonds on Cancer Cells
Sandeep Yadav, Sankalpa Gajanana Lotlecar, Prashant Singh and Pallavi Jain
Chapter 5 Graphene and GO: Synthesis and Characterization
Gourang Hari Gupta, Chetan Gawali, and Suveen Kumar
Chapter 6 Synthesis and Characterization of Graphene
Azad Kumar, Durgesh Chauhan, Kunvar Pratap Nishad, Ankur Prajapati, and Rahul Kushwaha
Chapter 7 Graphene and GO: Properties and Applications
Khushboo Gupta, O. P. Thakur and Manish Kumar
Chapter 8 Graphyne: Properties and Applications
Vaibhav Sharma, Piyush Gupta, and Shilpi Bansal
Chapter 9 Cancer Detection Utilizing Graphene-based Materials
Anjali Rani, Mohd Aslam, Javed Khan, Garima Pandey, and Bhaskara Nand Pant
Chapter 10 Electrochemical and Biosensor of Graphene-Based Materials for the Detection of Cancer
Mustapha Sulaiman, Ma’aruf Abdulmumin Muhammad, and Sapna Raghav
Chapter 11 New Horizons of GO-based Study for Diagnosis and Therapeutic Application of Cancer
Shilpi Bansal, Monika Bajpai, and Piyush Gupta
Chapter 12 Graphene Field-Effect Transistors (GFETs) for Cancer Diagnostics
Ujjwal Sharma, Anirudh Pratap Singh Raman, Pallavi Jain, and Prashant Singh
Chapter 13 Scalability and Manufacturing Challenges of Graphene Oxide and Graphyne
Javed Khan, Mohd. Aslam, Vaibhav Kumar Mishra, Ravinder Singh, Garima Pandey, and Bhaskara Nand Pant
Chapter 14 Integration with Clinical Practices: Graphene Oxide and Graphyne
Deepa, Madhur Babu Singh, Durgesh Kumar, Vijay K. Vishvakarma, Kumar Rakesh Ranjan, and Kamlesh Kumari
Chapter 15 Toxicology of Graphene, GO and Graphyne-based Materials
Pallavi Jain and Sunil Kumar Yadav
Chapter 16 Challenges and Limitations of Graphene Oxide and Graphyne as Biosensor in Detection of Cancer
Naina, Kumar Rakesh Ranjan, Garima Pandey, and Kamlesh Kumari
Chapter 17 Future Perspective of Graphene oxide and Graphyne in Detection of Various Diseases along with Cancer
Iona Massey, Sandeep Yadav, Vijay Vishvakarma, and Prashant Singh
Biography
Pallavi Jain, Ph. D., is working as an Associate Professor in the Department of Chemistry, SRM Institute of Science and Technology, Delhi-NCR Campus, Modinagar, Ghaziabad, India. Dr. Jain received her Ph.D. degrees in Chemistry from Banasthali Vidyapith, Rajasthan, India in 2017. She has extensive teaching experience of about 18 years. Her research interest focuses on the development of transition metal complexes of biological importance in drug delivery. Her research interests also focus on the synthesis of metal complexes as effective biosensors. She has authored and co-authored over 55 research publications in journals of international repute, and contributed more than 30 book chapters.
Chandrabhan Verma, PhD, is working in the Interdisciplinary Research Center for Advanced Materials, King Fahd University of Petroleum andMinerals, Dhahran, 31261, Saudi Arabia. He is a member of American Chemical Society (ACS). His research is mainly focused on the synthesis and designing of environmental friendly corrosion inhibitors useful for several industrial applications. Dr. Verma is the author of several research and review articles in peer-reviewed international journals of ACS, Elsevier, RSC, Wiley and Springer etc. He has total citation of more than 4582 with h-index of 36 and i-10 index of 86. Dr. Verma received several national and international awards for his academic achievements. Currently, Dr Verma is editing more than 15 books at the ACS, RSC, Wiley and Elsevier platforms.
Anirudh Pratap Singh Raman is doing Ph.D. from SRM Institute of Science & Technology, Ghaziabad. Ms. Raman has done her master’s from Amity University, Noida and graduated from Miranda House, University of Delhi. Her research focuses on investigating the non-covalently functionalized GO with eutectic mixture in sensing biological potential molecules. She has published 9 research papers and 12 review papers in peer-reviewed journals. She has a total citation of more than 190 with a H-index of 8 and an i-19 index of 9.
Kamlesh Kumari is currently working as Assistant Professor at Department of Zoology, University of Delhi since 2022. Earlier, she worked at Deen Dayal Upadhyaya College, University of Delhi, India for more than six years. She has published 90 research articles/ reviews/ chapters. The citations to her work are 1440 as per google scholar. h -index and i-10 index to her work are 21 and 50, respectively. She is currently working on computational biology, nanoparticles and exploration of graphene oxide in different areas.
Prashant Singh, Ph. D. is working as a Professor of Chemistry at Atma Ram Sanatan Dharam College, University of Delhi. He has completed four research projects from different funding agencies in India. Three students have received and seven research scholars are currently pursuing Ph.D. degree under his supervision. His area of research is to explore promising inhibitors against SARS-CoV-2 and CHIKV using molecular docking and molecular dynamics simulations. He also works on the exploration of C-based molecules like GO, and GDY in water remediation and others. He has published more than 200 research articles/reviews/preprints/chapters. The total citation to the work is more than 3400. The h-index and i-10 index credited to his work are 32 and 99 respectively. Prof. Singh has also significant experience in editing books from different publishers.
