1st Edition
Natural Scaffolds for Prevention and Treatment of Neurodegenerative Disorders
Neurodegenerative diseases affect millions of people worldwide and are a group of several diseases with distinct pathology, physiology, prevention, and treatment strategies. Recently, natural products especially derived from medicinal plants are gaining momentum to manage neurodegenerative disease safely and effectively. Therefore, an urgent need to provide a ready roadmap for the development of several value-added current research in this context.
Natural Scaffolds for Prevention and Treatment of Neurodegenerative Disorders will provide compiled information stating several identified neurodegenerative diseases including pathology and physiology. From vast literature on natural products including scientifically validated plant bioactive, from traditional approaches to combat or prevent such conditions are also included along with molecular mechanisms. The book will further specify:
- Single window complied information on various neurodegenerative diseases.
- Possible projection of bioactivity from natural resources to each category of neurodegenerative diseases.
- Ready to use reference material to develop several value-added products or proceed to the next level.
The book will be very useful for nutraceutical research groups, education institutions, and industries focusing on developing value-added solutions for the management of several neurodegenerative diseases.
Chapter 1: Current trends and future prospects of natural product in Neurodegenerative disorders
Neeraj K. Sethiya, Shikha Sharma, Kamal Shah, Durgesh Nandini Chauhan, Nagendra Singh Chauhan
Chapter 2: Natural bioactive used as memory enhancer
Ankur Balyan, Meenakshi Kaira, Vaibhav Walia
Chapter 3: Role of Natural Bioactives for their potential towards Anti-Parkinsonian Activity
N.V.L. Sirisha Mulukuri, Sushil Kumar Chaudhary, Pankaj Kumar, Burhanuddin Madriwala, N Venuka Devi
Chapter 4: Natural bioactive used as epilepsy activity
Santosh Kumar Rath, Gursharan Kaur, Palak Rana, Mittali, Vagish Dwibedi, Ranjana Prakash
Chapter 5: Natural bioactives used as anti-stress
Archana N Sah, Maneesha Pathak, Pooja Rawal, Devesh Tewari
Chapter 6: Bioactives in the treatment of mood disorders
Ankur Balyan, Meenakshi Kaira, Vaibhav Walia
Chapter 7: Natural bioactive used for Alzheimer’s and other dementias
Anshul Shakya, Bhargab Deka, Shuby Kumari, Sushil Kumar Chaudhary, Shweta Maurya, Amit Kumar, Hans Raj Bhat, Surajit Kumar Ghosh
Chapter 8: Natural bioactive used for Multiple sclerosis
Shiv Shankar Shukla, Varsha Sahu, Neha Dubey, Nagendra Singh Chauhan, Vishal Jain, Amber Vyas, Ravindra Kumar Pandey, Bina Gidwani
Chapter 9: Natural bioactive used for Meningitis
Varsha Sahu, Rahul Kumar, Neha Dubey, Ravindra Kumar Pandey, Shiv Shankar Shukla, Nagendra Singh Chauhan, Riya Vaswade, Amber Vyas, Bina Gidwani
Chapter 10 Natural Bioactive Molecules as Neuromedicines for the Treatment & Prevention of Huntington's Disease
Yash Jasoria, Mohit Agrawal, Manmohan Singhal, Hema Chaudhary, Md Sadique Hussain, Shivendra Kumar, Neha Minocha
Chapter 11: Natural Bioactives Used For Japanese Encephalitis
Bhavna Kumar, Khusbhoo Bansal, Shraddha Singh Raghav, Ganesh Chandra Sahoo, Maneesh Kumar, Swati arya, Neeraj Kumar Sethiya, Manmohan Singhal, Samir Bhargava, Vijay Singh Rana, Abhijeet Ojha
Chapter 12 Natural Bioactive used for Cerebrovascular Disease
Anupam Jaiswal, Megha Verma ,Shantilal Singune
Chapter 13 Multifaceted impact of the resveratrol on the neurological disorders
Anshul Shakya, Shuby Kumari, Sheikh Rezzak Ali, Sushil Kumar Chaudhary, Anuradha Thakur, Motlalepula Matsabisa, Hans Raj Bhat, Surajit Kumar Ghosh
Chapter 14 Flavonoids as natural multi-targeting scaffolds for the management of Alzheimer’s disease
Anand Ganapathy A, Vijayakumari Mahadevan Hari Priya, Alaganandam Kumaran
Chapter 15 Phytochemicals for the treatment of CNS disorders
Vrishti Thakur, Sangeeta Dwivedi, Steffy Mary Chandy, Renuka Maru, Kamal Shah, Nagendra Singh Chauhan, Rakhi Khabiya, Saurabh Maru
Chapter 16 Use of plant based scaffolds for carrying dental stem cells for treatment of neurodegenerative disorders
Pearlcid Siroraj, Saranya Varadarajan, Rajeswari Ramesh, Jawahar Babu, Thomson Mariadasan D’Cruz, Deepak Moses Ravindran, Karthick Sekar, ThodurMadapusi Balaji
Chapter 17 Shankhpushpi: A promising remedy for neurodegenerative disorders
Soniya Kamat, Renuka Maru, Vanraj Shirsath, Mahendra Kumar Prajapati, Amit Pandit, Kamal Shah, Nagendra Singh Chauhan, Saurabh Maru
Chapter 18 Phytochemistry and pharmacological activities of Bacopa monnieri against neurodegenerative diseases
Shiv Bahadur, Somya Chauhan, Medha Arya, Kamal Shah
Chapter 19 Acorus calamus in Neurodegenerative Disorders
Sanjay Kumar Gupta, Astha Verma, Nikita Verma, Kamal Shah, Durgesh Nandini Chauhan, Nagendra Singh Chauhan
Chapter 20 St. John’s Wort: A Comprehensive account of preclinical and clinical evidences for treatment of neurodegenerative disorders
Tanya Joshi, Pushkar Desale, Mahaveer Singh, Vijay Chidrawar, Kamal Shah, Nagendra Singh Chauhan, Renuka Maru, Saurabh Maru
Chapter 21 Neuroprotective effect of potential phytochemicals in the prevention of neurodegenerative diseases
Unnati Darak, Priyatosh Ranjan, Parth Sarthi Sen Gupta
Biography
Dr. Neeraj Kumar Sethiya is currently working as an Associate Professor at Faculty of Pharmacy, DIT University, Dehradun. He has a total of 16 years of experience of teaching, research and innovation.Dr. Sethiya completed his PhD (Pharmacy) in March, 2012 from The MS University of Baroda, Vadodara, Gujarat, India and M.Pharm (Pharmacognosy) from Dr. H. S. Gour Central University Sagar, MP, India. He is recipient of many acclaimed awards. He is also currently handling industrial and Govt funded project. During his tenure, he published 68 reputed scientific papers, 13 Book Chapters, 7 Books, 20 patents (6 Granted and 14 Published) and Supervised 1 PhD student.His major research includes target-oriented and lead-based design and development of New Chemical Entities (NCEs) from natural scaffolds against Anti-stress, Anxiolytic, Anti-arthritis, Antidiabetic, Antioxidant, Alzheimer’s, Antimalarial, Hepatoprotective andAntiurolithiatic. He is currently working on the area of herbal nutraceuticals, herbal cosmetics and value-added product development from organic waste, He framed the curriculum and introduced Clinical Pharmacognosy, first time as an added subject for B. Pharm students at DIT University. Besides teaching pharmacognosy and natural product chemistry, he has also hands-on domain and expertise on innovation, entrepreneurship, patents, and NBA approval.
Additionally, Dr. Sethiya has been enlisted as world top 2% Scientist List jointly declared by Stanford University and Elsevier for the last three consecutive years. He has been Honoured as Editor in Chief for Bentham Sciences Journal Current Indian Sciences- Natural Product. Recently, Dr. Sethiya has been appointed as Reviewer Credit Ambassador of India.
Durgesh Nandini Chauhan, MPharm, has several years of academic (teaching) experience at institutes in India in pharmaceutical sciences working in Columbia College of Pharmacy, Raipur CG India. She taught subjects as pharmaceutics, pharmacognosy, traditional concepts of medicinal plants, drug delivery, phytochemistry, cosmetic technology, pharmaceutical engineering, pharmaceutical packaging, quality assurance, dosage form designing, and anatomy and physiology. She is a member of the Association of Pharmaceutical Teachers of India, SILAE: Società Italo-Latinoamericana di Etnomedicina (The Scientific Network on Ethnomedicine, Italy), and others. She has attended several workshops, conferences, and symposiums, including the AICTE-Sponsored Staff Development Program on “Effects of Teaching and Learning Skills in Pharmacy: Tool for Improvement of Young Pharmacy Teachers.” She has written more than ten articles published in national and international journals, 15 book chapters, and editors in 10 books. She is also active as a reviewer for several international scientific journals and an active participant at national and international conferences, including Bhartiya Vigyan Sammelan and the International Convention of Society of Pharmacognosy. Presently she joined Ishita Research Organization, Raipur, India as a freelance writer and guide for students in pharmacy, Ayurvedic, and science in their research projects. She would be interested in data analysis, proposal writing, questionnaire design, designing and developing research questionnaires and policy. She would be actively engaged with accurately monitoring, investigating and analyzing all statistical information, professionally presenting information, reports and investigating and documenting key data and information at the request of senior researchers.
Dr. Nagendra Singh Chauhan obtained his M.Pharm, Ph.D. from the Department of Pharmaceutical Sciences, Dr. H.S. Gour University, Sagar, MP, India. He has around 20 years of research experience. He is presently working as a Senior Scientific Officer Grade-I and Government Analyst at Drugs Testing Laboratory Avam Anusandhan Kendra, Raipur, Chhattisgarh, India. He has professional expertise in Natural Product Isolation and phytopharmacology. He has written more than 70 articles published in national and international journals and 32 book chapters and edited 7 books. Recipient of Dr. P. D. Sethi Memorial National Award for the best HPTLC publication from India in the year 2021 and 2022. He is a member of various professional and academic bodies like the Society of Pharmacognosy India, the International Natural Product Sciences Taskforce (INPST) society, SILAE: Società Italo-Latinoamericana di Etnomedicina (The Scientific Network on Ethnomedicine, Italy), Institutional Human ethical committee, Association of Pharmaceutical Teachers of India (APTI), and Indian Pharmacy Graduates' Association.
Dr. Kamal Shah has more than 18 years of research and teaching experience and currently working as Professor at the Institute of Pharmaceutical Research, GLA University, Mathura,
India. He has completed B.Pharma from Rajiv Gandhi Proudyogiki Vishwavidyalaya, Bhopal (M.P.) in 2003. He was gold medalist in B.Pharm., M.Pharm. from the Department of Pharmaceutical Sciences, Sagar University, Sagar, India and PhD from APJ Kalam University Lucknow, India. He has written more than 90 articles published in national and international journals, 20 book chapters and 05 edited books. His SCOPUS h index is 17, with 905 citations.
